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What is Apligraf®?What is Apligraf®?How does Apligraf® Compare?
Apligraf® is:
  • FDA Approved:
    Apligraf® is an FDA approved product that has been evaluated in multiple controlled clinical studies and is proven to be effective, safe, and to accelerate healing. Many wound care products cannot make such claims.
  • Superior healing compared to basic wound care:
    Apligraf® heals more wounds (30% to 50% more) and heals them faster (in 1/3 less time).
  • Active vs. passive wound healing:
    Many wound therapies are designed to passively manage the wound. Apligraf® plays a more active role by delivering to the wound living cells, proteins produced by the cells, and collagen, which are important for healing as growth factors, cells, and proteins directly to the wound.
  • A living therapy similar to our own skin:
    Apligraf® is the only living cell based treatment containing two different types of skin cells combined with collagen, and is close in structure to natural human skin.
  • Easy:
    Apligraf® typically requires no daily maintenance. Dressings are usually changed once a week by your doctor or nurse, depending on your wound type.


3. Falanga V, Sabolinski ML. A bilayered living skin construct (Apligraf®) accelerates complete closure of hard-to-heal venous ulcers. Wound Repair Regen. 1999;7:201-207.

4. Veves A, Falanga V, et al. Graftskin, a human skin equivalent, is effective in management of non-infected neuropathic diabetic foot ulcers. Diabetes Care. 2001;24:290-295