Apligraf Case Study – Venous Leg Ulcer 3 Months' Duration
Patient: 71-year-old female
Wound: Venous leg ulcer of approximately 3 months duration
Prior Treatment: Compression therapy with Unna's boot
Apligraf Application: Apligraf was applied to the wound. Compression therapy was initiated and maintained throughout the treatment.
The case presented here represents the experience of a single patient and may not be typical of all patients. Apligraf® should not be used on infected wounds or on patients with known hypersensitivities to any components of Apligraf. Please consult the complete prescribing information for a description of epidermal and dermal elements contained in Apligraf.
Day 0
Appearance of the wound bed prior to Apligraf. Granulation tissue is evident. Wound measured 2.5 cm in length and 1.3 cm in width.
Week 1
Wound has decreased in size to 0.63 cm in length by 0.32 cm in width. Second Apligraf applied to stimulate additional healing.
Week 2
Apligraf appears to have “taken,” demonstrating revascularization and healing. The epithelium is fully differentiated into a stratum corneum just like the patient’s own skin.
Week 52
The wound remains completely healed. Remodeling of the wound has taken place, with evidence of repigmentation.