Apligraf Case Study – Edge Effect / New Tissue Formation
Patient: 74-year-old female
Wound: Venous leg ulcer of approximately 3 months duration
Prior Treatment: Hydrocolloid dressing plus elastic compression wrap and topical antibiotics
Apligraf Application: Apligraf was applied to the wound and dressed with non-adherent dressing in elastic wrap (Coban™).
The case presented here represents the experience of a single patient and may not be typical of all patients. Apligraf® should not be used on infected wounds or on patients with known hypersensitivities to any components of Apligraf. Please consult the complete prescribing information for a description of epidermal and dermal elements contained in Apligraf.
Day 0
Wound debrided and ready for Apligraf. Wound measures 2.0 cm in width by 3.5 cm in length. Granulation tissue is evident.
Week 3
Wound area reduced in size. Additional granulation tissue evident at wound edge.
Week 5
Wound is completely healed.
Week 20
Wound continues to remodel, with possible signs of repigmentation. No recurrence observed.