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Venous Leg Ulcer

Significantly More Effective Than Compression Therapy Alone in All Patients

  • Apligraf® plus compression therapy was more effective in achieving complete wound closure by week 24 (57% vs 40%, P=.022)

All Patients Achieving 100% Closure*

By 12 Weeks

More Than Twice as Effective as Compression Therapy Alone in Long-Standing Ulcers

  • In patients with ulcers >1 year's duration (n=120), Apligraf plus compression therapy was more than twice as effective in achieving complete wound closure by week 24 (47% vs 19%, P=.002)1 These data compare with 66% vs 73% (Apligraf vs. control), P=.434 for patients with ulcers <1 year's duration (n=120)

Package Insert
*Cox Proportional Hazards Regression Analysis used to adjust for pooled data and factors known to impact wound healing, which include baseline ulcer area and ulcer duration.

References:
1. Falanga V, Sabolinski ML. A bilayered living skin construct (Apligraf®) accelerates complete closure of hard-to-heal venous ulcers. Wound Repair Regen. 1999. In press.