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Venous Leg Ulcer

Significantly More Effective Than Compression Therapy Alone in All Patients

  • Apligraf® plus compression therapy was more effective in achieving complete wound closure by week 24 (57% vs 40%, P=.022)

All Patients Achieving 100% Closure*

By 12 Weeks

More Than Twice as Effective as Compression Therapy Alone in Long-Standing Ulcers

  • In patients with ulcers >1 year's duration (n=120), Apligraf plus compression therapy was more than twice as effective in achieving complete wound closure by week 24 (47% vs 19%, P=.002)1 These data compare with 66% vs 73% (Apligraf vs. control), P=.434 for patients with ulcers <1 year's duration (n=120)

Package Insert
*Cox Proportional Hazards Regression Analysis used to adjust for pooled data and factors known to impact wound healing, which include baseline ulcer area and ulcer duration.

1. Falanga V, Sabolinski ML. A bilayered living skin construct (Apligraf®) accelerates complete closure of hard-to-heal venous ulcers. Wound Repair Regen. 1999. In press.